Product Classification

Gluten-Free

No Detectable GMO

Vegan

Isotonic

Good Manufacturing Practices

Dairy Free
Directions for Use

Pour 1 small capful (3.3 g) of powder into a cup.

Add water 2 fl. oz/60 mL of water for each capful and stir.

Enjoy once a day. For maximum absorption take on an empty stomach.
Key Ingredients & Benefits

Grape Seed Extract
Grape skin extract is a potent antioxidant. The antioxidant properties of grape skin extract contribute to maintaining healthy circulation by strengthening capillaries, arteries and veins, and promoting overall cardiovascular health.

Grape Skin Extract
Grape skin extract is a potent antioxidant. The antioxidant properties of grape skin extract contribute to maintaining healthy circulation by strengthening capillaries, arteries and veins, and promoting overall cardiovascular health.and promoting overall cardiovascular health.

Bilberry Extract
Extracts of the ripe berry are known to contain flavonoid pigments known as anthocyanins, which are powerful antioxidants. Scientific studies confirm that bilberry extract supports venous circulation. Bilberry extract helps maintain healthy circulation by strengthening capillaries, arteries and veins.

Citrus Extract (Bioflavaniods)
Bioflavonoids have been found to promote cardiovascular health, while helping to maintain healthy circulation by strengthening capillaries, arteries and veins.
Powerful Antioxidant Supplement: Isotonix OPC-3®
Isotonix OPC-3® Supports blood vessel function, Helps maintain healthy cholesterol and blood glucose levels, Promotes cardiovascular and joint health, and Supports a healthy complexion at every level!
Isotonix Delivery System

:05 Minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.

:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What is a bioflavonoid?
Bioflavonoids are complex organic plant compounds. Plants and fruits differ in colors based on the specific bioflavonoids they contain. An increasing number of studies have shown how bioflavonoids support health. Bioflavonoids found in OPCs play a key role in cardiovascular health and maintaining vascular integrity. Bioflavonoids have been shown to demonstrate support for healthy circulation and cell vitality.
What sets Isotonix OPC-3 apart from other bioflavonoid products?
Isotonix OPC-3 offers scientifically supported OPCs. In addition to being antioxidants, these individual OPCs have been shown to provide a myriad of specific health benefits. This science-driven selection of OPCs is unique to OPC-3, as is the Isotonix delivery system, which enables rapid and highly efficient absorption of the OPCs.
How should I take OPC-3?
OPC-3 is for ADULT USE ONLY. Pour one (1) level, white bottle capful of powder into the overcap. Add water to the line on the overcap (2 fl. oz/60 ml) and stir. As a dietary supplement take once daily or as directed by your healthcare provider. Take two (2) capfuls per 68 kg of body weight daily for the first 7-10 days, and take 1 capful thereafter as a maintenance program. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amounts of powder and water are used.
How long does it take to benefit from Isotonix OPC-3?
Many effects of OPC-3 start to work after a single serving. OPC-3 not only provides some of the most potent OPCs available, the unique Isotonix delivery system ensures that the small intestine rapidly absorbs the OPCs, which are available in the blood stream within minutes. Taking Isotonix OPC-3 daily enables the body to sustain a consistent antioxidant defense.
Why should everyone take Isotonix OPC-3?
Free radical damage and oxidative stress everyone is subject to. Free radicals develop as byproducts of physiological processes that occur within the body. This damage does not cause noticeable harm at first, yet may add up over the years. This process is largely responsible for the aging process. Free radicals have been linked directly to premature ageing, poor circulation, poor heart health and poor immune health. OPCs are the most powerful natural free radical neutralizers. Daily, regular use is vital for keeping free radicals in check.
Can you take Isotonix OPC-3 in soda, juice, coffee, etc., rather than water?
It is possible but not recommended. This product should only be taken as directed. In order to keep the product in an isotonic form and to achieve the maximum delivery speed, it needs to be taken on an empty stomach with 2 oz./ 60 ml of water per capful. Mixing the products with anything else besides other Isotonix products and water slows down the delivery time and may affect the percentage of uptake.
I am healthy and athletic, why should I take Isotonix OPC-3?
Everyone is vulnerable to the aging process caused by continuous free radical damage. Athletes tend to be exposed to elevated levels of oxidative stress. Free radicals develop as byproducts during metabolism when calories are processed with oxygen. The increase in activity creates additional free radicals. In fact, these free radicals are known to limit performance, as free radicals appear to take their toll on muscle tissue.
Does OPC-3 have visible benefits?
As OPCs support collagen production in the skin, an increase of smoothness and support of elasticity is the natural result. Skin smoothness was increased after three months as measured by 3-dimensional topography. It requires patience to show visible effects. It is essential to continuously take OPC-3 to keep skin cells at their peak vitality. On a short-term basis, many people notice a fresher-looking skin complexion. This is a result of healthy blood microcirculation, which helps detoxify the skin and improves the nutrient supply.
What are the cardiovascular health benefits of OPCs?
Scientist Albert Szent-Gyorgyi, who received the Nobel Prize for the discovery of vitamin C, discovered OPCs. Szent-Györgyi found that OPCs work in a similar fashion as vitamin C in that strengthen the walls of arteries, veins and capillaries.* In the past 20 years scientists discovered that OPCs bear a lot more benefits for the cardiovascular system. Epidemiological studies have shown that regular intake of OPC antioxidants supports a healthy cardiovascular system. OPCs appear to be particularly helpful in maintaining healthy cholesterol levels and healthy arteries. Pycnogenol in Isotonix OPC-3 plays a key role, as it promotes healthy nitric oxide (NO) levels. NO is a tiny molecule which serves as a key messenger molecule in the blood stream. It promotes relaxation of smooth muscle-surrounding arteries and supports normal artery diameter and blood flow. Healthy NO levels help maintain normal blood pressure. This benefit has been explicitly demonstrated with Pycnogenol in studies. NO also promotes healthy blood platelet activity thus preserving a normal, fluid environment and thereby promotes cardiovascular health.*
What exactly is Pycnogenol?
Pycnogenol is the trademark of Horphag Research (UK) Ltd. for a standardized extract of bark of the French maritime pine tree. Pycnogenol is particularly renowned for its extensive clinical research with more than 120 studies published in peer-reviewed medical journals. The flavonoids in Pycnogenol not only act as powerful antioxidants, they also appear to promote the normal generation of nitric oxide (NO). NO plays a key role in regulating cardiovascular health. Nitric oxide promotes the normal relaxation of arteries, supports normal diameter of blood vessels and helps maintain healthy blood pressure and circulation. NO promotes normal platelet activity allowing the blood to maintain a normal, fluid viscosity. Pycnogenol has been awarded various patents for its ability to support healthy platelet activity.*
Reviews
Customer Rating
4.8 out of 5 star rating.
(223 reviews)
would recommend this product.
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Isotonix OPC-3 impacted my beloved bunny, Bueno. In September 2024, I found a lump on his neck, and the vet suggested amputation. I couldn’t bear to put him through that. In November 2025, I reached out to Verna, who kindly gave me OPC-3 to try. I mixed it with water and fed him 3 mL three times a day. To my surprise, OPC-3 helped my bunny and improved my own energy. His lump shrank by 50%. We had precious extra time together, and I’m forever thankful. Sadly, Bueno passed away on 31 January 2025, but I’ll always cherish our time. I recommend OPC-3 to all bunny owners as a preventive supplement.
Amazing OPC
by WillL
on 31/3/2025
OPC amazingly helps me to cope with my Sinus. I hardly get the attack nowadays.
Great product
by KeithW
on 28/3/2025
I've been taking the OPC-3 daily for the past few years and I found that it greatly helped with my morning sinuses. In addition, I took quite a liking to the taste.
I love OPC
by Yasuki
on 5/3/2025
Great product, and I really enjoy the service provided by Annie Lee. She's such an amazing person who's not only understanding the product well, but her care is beyond. She's someone I can always rely on if I want to understand more about this product. Thank you, Annie ❤️
The must have supplement in my routine now
by HowR
Shop Consultant
on 4/2/2025
I started taking OPC-3 a few months ago after researching natural ways to support healthy blood pressure. Along with diet and exercise, I've incorporated OPC-3 into my daily routine. I've been monitoring my blood pressure regularly, and I've been happy to see it trending in a healthy direction. I feel OPC-3 has been a valuable addition to my wellness regimen.'
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